Tracheal telocytes

Journal of Cellular and Molecular Medicine

M. C. Rusu¹  Adelina M. Jianu⁵  N. Mirancea³  Andreea C. Didilescu⁴  V. S. Mănoiu² 

[1] Division of Anatomy, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania;Department of Cellular and Molecular Biology, National Institute of Research and Development for Biological Sciences, Bucharest, Romania;Plant and Animal Cytobiology Department, Institute of Biology – Romanian Academy, Bucharest, Romania;Division of Embryology, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania;Department of Anatomy, Faculty of Medicine, “Victor Babeş” University of Medicine and Pharmacy, Timisoara, Romania

关键词: telocytes;    telopodes;    mast cells;    interstitial cells;    stromal cells;    primary cilium;   

DOI  :  10.1111/j.1582-4934.2011.01465.x

来源: Wiley

【 摘 要 】

Abstract

Recently, a novel type of stromal cell – the telocytes (TC) – was identified in mouse trachea. These cells are known to possess the ultrastructural characteristics, which support their role in intercellular signaling. We found TC in all stromal compartments of the tracheal wall. TC with long prolongations (telopodes, Tp) were lining longitudinally the collagen bundles, and were serially arranged (end-to-end connections of Tp were found). Noteworthy, Tp frequently establish stromal synapses with mast cells (MC). Primary cilia were also identified in TC. In conclusion, tracheal TC could be involved in the tracheal regulation (e.g. secretion, contractility). The tandem TC-MC deserves further investigations.

【 授权许可】

Unknown   
© 2011 The Authors Journal of Cellular and Molecular Medicine © 2011 Foundation for Cellular and Molecular Medicine/Blackwell Publishing Ltd