The Global Influenza Hospital Surveillance Network (GIHSN): a new platform to describe the epidemiology of severe influenza

Influenza and Other Respiratory Viruses

Joan Puig-Barberà⁶  Anita Tormos⁶  Svetlana Trushakova⁵  Anna Sominina¹  Maria Pisareva¹  Meral A. Ciblak⁴  Selim Badur⁴  Hongjie Yu³  Benjamin J. Cowling²  Elena Burtseva⁵ 

[1] Research Institute of Influenza, St. Petersburg, Russian Federation;Li Ka Shing Faculty of Medicine, School of Public Health, The University of Hong Kong, Hong Kong, China;Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China;National Influenza Reference Laboratory Capa-Istanbul, Istanbul, Turkey;D.I. Ivanovsky Institute of Virology, Moscow, Russian Federation;Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valenciana (FISABIO), Valencia, Spain

关键词: Hospital;    influenza epidemiology;    surveillance network;   

DOI  :  10.1111/irv.12335

来源: Wiley

【 摘 要 】

Abstract

Background

Influenza is a global public health problem. However, severe influenza only recently has been addressed in routine surveillance.

Objectives

The Global Influenza Hospital Surveillance Network (GIHSN) was established to study the epidemiology of severe influenza in consecutive seasons in different countries. Our objective is to describe the GIHSN approach and methods.

Methods

The GIHSN uses prospective active surveillance to identify consecutive influenza admissions in permanent residents of well-defined geographic areas in sites around the world. A core common protocol is followed. After consent, data are collected on patient characteristics and clinical outcomes, respiratory swabs are obtained, and the presence of influenza virus and subtype or lineage is ascertained by polymerase chain reaction. Data are collated and analyzed at the GIHSN coordination center.

Results

The GIHSN has run its activities for two consecutive influenza seasons, 2012–2013 and 2013–2014, and hospitals in Brazil, China, France, Russian Federation, Turkey, and Spain have been involved in one or both seasons. Consistency on the application of the protocol and heterogeneity for the first season have been addressed in two previous publications. During both seasons, 19 677 eligible admissions were recorded; 11 843 (60%) were included and tested, and 2713 (23%) were positive for influenza: 991 (37%) A(H1N1); 807 (30%) A(H3N2); 583 (21%) B/Yamagata; 56 (2%) B/Victoria and 151 (6%) influenza A; and 125 (5%) influenza B were not characterized.

Conclusions

The GIHSN is a platform that provides information on severe influenza worldwide, applying a common core protocol and a consistent case definition.

【 授权许可】

CC BY   
© 2015 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.