Contribution of influenza to acute exacerbations of chronic obstructive pulmonary disease in Kashmir, India, 2010–2012

Influenza and Other Respiratory Viruses

Parvaiz A. Koul¹  Umar H. Khan¹  Romana Asad¹  Rubaya Yousuf¹  Shobha Broor³  Renu B. Lal² 

[1] Department of Internal & Pulmonary Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India;Influenza Division, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA;All India Institute of Medical Sciences, New Delhi, India

关键词: Chronic obstructive lung disease;    chronic obstructive;    hospitalization;    influenza viruses;    pulmonary disease;   

DOI  :  10.1111/irv.12291

来源: Wiley

【 摘 要 】

Abstract

We estimate the contribution of influenza to hospitalizations for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in Kashmir, India. Prospective surveillance for influenza among patients hospitalized with AECOPD was conducted at a tertiary care hospital. Patients had clinical data collected and nasal/throat swabs tested for influenza viruses. Outcomes among patients with and without influenza were compared with logistic regression adjusting for age and underlying conditions. During October 2010–September 2012, 498 patients hospitalized with AECOPD were enrolled, of whom 40 (8%) had received influenza vaccine. Forty (8%) had influenza; influenza virus detection peaked in winter (January–March). Patients with influenza were more likely to die during hospitalization (adjusted OR 3·4, CI 1·0–11·4) than those without.

【 授权许可】

CC BY   
© 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.