Sentinel surveillance of influenza in Burkina Faso: identification of circulating strains during 2010–2012

Influenza and Other Respiratory Viruses

Zékiba Tarnagda²  Issaka Yougbaré¹  Abdoul K. Ilboudo²  Thérèse Kagoné³  Armel M. Sanou²  Assana Cissé²  Isaïe Médah⁴  Denis Yelbéogo⁴ 

[1] St. Michael's Hospital LKSKI - Keenan Research Centre, Toronto, ON, Canada;Institut de Recherche en Sciences de la Santé, Centre National de Référence pour la Grippe, Bobo-Dioulasso, Burkina Faso;Centre Muraz, Bobo-Dioulasso, Burkina Faso;Direction de la lutte contre la maladie (DLM), Ministère de la santé, Ouagadougou, Burkina Faso

关键词: Burkina Faso;    influenza‐like illness;    sentinel surveillance;   

DOI  :  10.1111/irv.12259

来源: Wiley

【 摘 要 】

Abstract

Background

Although influenza surveillance has recently been improved in some sub-Saharan African countries, no information is yet available from Burkina Faso.

Objectives

Our study was the first to determine the prevalence of influenza viruses circulating in Burkina Faso through a sentinel surveillance system.

Methods

We conducted sentinel surveillance with oropharyngeal (OP) swabs collected from outpatients (1 month to 83 years) from six sites in Bobo-Dioulasso and Ouagadougou, among patients meeting the WHO/CDC case definition for influenza-like illness (ILI; fever ≥38°C, and cough and/or sore throat in the absence of other diagnosis) from July 2010 to May 2012. Influenza viruses were detected by real-time RT-PCR using CDC primers, probes, and protocols.

Results

The first three ILI cases were enrolled each day; of 881 outpatients with ILI enrolled and sampled, 58 (6·6%) tested positive for influenza viruses (29 influenza A and 29 influenza B). Among the influenza A viruses, 55·2% (16/29) were influenza A (H1N1)pdm09 and 44·8% (13/29) were seasonal A (H3N2). No cases of seasonal A/H1N1 were detected. Patients within 0–5 years and 6–14 years were the most affected, comprising 41·4% and 22·4% laboratory-confirmed influenza cases, respectively. Influenza infections occurred during both the dry, dusty Harmattan months from November to March and the rainy season from June to October with peaks in January and August.

Conclusions

This surveillance was the first confirming the circulation of influenza A (H1N1)pdm09, A/H3N2, and influenza B viruses in humans in Burkina Faso.

【 授权许可】

CC BY   
© 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.