Revised and updated nomenclature for highly pathogenic avian influenza A (H5N1) viruses

Influenza and Other Respiratory Viruses

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关键词: H5N1;    hemagglutinin;    highly pathogenic avian influenza;    molecular epidemiology;    nomenclature;    phylogenetics;    viral evolution;   

DOI  :  10.1111/irv.12230

来源: Wiley

【 摘 要 】

Abstract

The divergence of the hemagglutinin gene of A/goose/Guangdong/1/1996-lineage H5N1 viruses during 2011 and 2012 (807 new sequences collected through December 31, 2012) was analyzed by phylogenetic and p-distance methods to define new clades using the pre-established nomenclature system. Eight new clade designations were recommended based on division of clade 1·1 (Mekong River Delta), 2·1·3·2 (Indonesia), 2·2·2 (India/Bangladesh), 2·2·1·1 (Egypt/Israel), and 2·3·2·1 (Asia). A simplification to the previously defined criteria, which adds a letter rather than number to the right-most digit of fifth-order clades, was proposed to facilitate this and future updates.

【 授权许可】

CC BY   
© 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.