Spread of different rhinovirus B genotypes in hospitalized children in Spain

Influenza and Other Respiratory Viruses

María Teresa Cuevas²  Mar Molinero²  Francisco Pozo²  Cristina Calvo¹  Maria Luz García-García¹  Noelia Reyes²  Juan Ledesma² 

[1] Department of Pediatrics, Hospital Severo Ochoa, Leganés, Madrid, Spain.;Influenza and Respiratory Virus Laboratory, National Center for Microbiology, ISCIII.

关键词: Genotype;    human rhinovirus;    pediatric patients;    respiratory infection;   

DOI  :  10.1111/irv.12061

来源: Wiley

【 摘 要 】

Abstract

Please cite this paper as: Cuevas et al. (2013) Spread of different rhinovirus B genotypes in hospitalized children in Spain. Influenza and Other Respiratory Viruses 7(5), 623–628.

Human Rhinovirus (HRV) classification is an evolving process. New genotypes have been described within HRV-A and HRV-C species, but only one has been accepted related to HRV-B. From 2003 to 2010, a total of 3987 nasopharyngeal aspirate samples were taken from pediatric patients admitted to the Severo Ochoa Hospital in Madrid (Spain). After viral analysis, 949 (23·8%) tested positive to HRV. A random selection of 397 (42%) positive samples showed that 39 (9·8%) were HRV-B. The sequencing of partial VP4/VP2 coding region revealed the spread of 13 of 25 defined HRV-B serotypes and three putative new genotypes. Such results remark the high diversity of HRV-B.

【 授权许可】

Unknown   
© 2012 John Wiley & Sons Ltd