Burkholderia pseudomallei in cystic fibrosis and treatment complications

Respirology Case Reports

Naghmeh Radhakrishna¹ 

[1] Monash Medical Centre, Melbourne, Victoria, Australia

关键词: Burkholderia pseudomallei;    cystic fibrosis;    melioidosis;   

DOI  :  10.1002/rcr2.86

来源: Wiley

【 摘 要 】

Abstract

A healthy 29-year-old Australian man with cystic fibrosis (CF) grew Burkholderia pseudomallei on a routine sputum culture 1 month after returning from holiday in Thailand. He underwent a 12-month treatment regime with multiple antibiotics resulting in a number of adverse events. Sputum cultures were cleared of the pathogen and remain negative 8 years post-treatment. There were no clinical sequelae and no deterioration in lung function. Few reports have been published to date on melioidosis in CF patients. The proposed management for this infection includes multiple antibiotics regimens for prolonged periods of time, which may result in adverse events. Optimal treatment and length of treatment are currently determined on an individual basis.

【 授权许可】

CC BY-NC   
© 2014 The Authors. Respirology Case Reports published by John Wiley & Sons Ltd on behalf of The Asian Pacific Society of Respirology.

Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.