Mycobacterium abscessus – to treat or not to treat

Respirology Case Reports

Yong-Kek Pang²  Yun-Fong Ngeow¹  Yan-Ling Wong¹ 

[1] Department of Medical Microbiology, Faculty of Medicine, University of Malaya Medical Centre, University of Malaya, Kuala Lumpur, Malaysia;Department of Medicine, Faculty of Medicine, University of Malaya Medical Centre, University of Malaya, Kuala Lumpur, Malaysia

关键词: Indolent infection;    Mycobacterium abscessus;    non‐tuberculous mycobacterium;    sensitivity test;    treatment regimen;   

DOI  :  10.1002/rcr2.17

来源: Wiley

【 摘 要 】

Abstract

A patient with Mycobacterium abscessus lung disease was mistaken to have pulmonary tuberculosis with airway colonization by the non-tuberculous mycobacterium. Appropriate antibiotics were only given when the patient's signs and symptoms worsened while on anti-tuberculosis therapy. Despite treatment with a combination of antibiotics showing in vitro susceptibility, the pathogen persisted in the respiratory secretions for longer than 6 months and the patient suffered a spontaneous pneumothorax 14 months into treatment. This case illustrates the chronic course of M. abscessus lung infection, the tendency for flare-ups, the inadequacy of current treatment regimens, and the necessity for prolonged patient follow-up.

【 授权许可】

CC BY-NC-ND   
© 2013 The Authors. Respirology Case Reports published by John Wiley & Sons Ltd on behalf of The Asian Pacific Society of Respirology.

Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.