Advanced right lung adenocarcinoma with ipsilateral breast metastasis

Respirology Case Reports

Chong-Kin Liam²  Yong-Kek Pang²  Mau-Ern Poh¹  Ken-Siong Kow¹  Chee-Kuan Wong¹ 

[1] Department of Medicine, University of Malaya Medical Centre, Kuala Lumpur, Malaysia;Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

关键词: Breast;    lung adenocarcinoma;    metastasis;   

DOI  :  10.1002/rcr2.14

来源: Wiley

【 摘 要 】

Abstract

Breast metastases from non-small cell lung carcinoma are rarely reported. We report a case of a female patient with primary adenocarcinoma of the lower lobe of her right lung presenting with a massive right-sided malignant pleural effusion. The tumor harbored an epidermal growth factor receptor insertion mutation in exon 20 but was anaplastic lymphoma kinase translocation negative. She did not respond to treatment with erlotinib. First- and second-line cytotoxic chemotherapy resulted in stable disease as the best responses. She developed right breast metastasis 20 months after her initial presentation. The rarity of the condition and the likely mechanism of the breast metastasis are discussed.

【 授权许可】

CC BY-NC   
© 2013 The Authors. Respirology Case Reports published by John Wiley & Sons Ltd on behalf of The Asian Pacific Society of Respirology.

Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.