Severe respiratory failure associated with influenza B virus infection

Respirology Case Reports

Shinpei Kato¹  Tomoyuki Fujisawa¹  Noriyuki Enomoto¹  Naoki Inui²  Yutaro Nakamura¹ 

[1] Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan;Department of Clinical Pharmacology and Therapeutics, Hamamatsu University School of Medicine, Hamamatsu, Japan

关键词: ARDS;    diffuse alveolar damage;    influenza;    pneumonia;    respiratory failure;   

DOI  :  10.1002/rcr2.107

来源: Wiley

【 摘 要 】

Abstract

A 72-year-old man who had been diagnosed with type B influenza infection and high fever 4 days previously was admitted to our hospital. He presented with severe respiratory insufficiency; chest computed tomography (CT) revealed extensive ground-glass opacity in lung fields on both sides. Although peramivir and antibiotics were administered, reticular shadows on chest CT worsened and respiratory insufficiency deteriorated. The patient fulfilled the criteria for severe acute respiratory distress syndrome. Despite multimodal therapy, including noninvasive positive pressure ventilation, polymyxin B-immobilized fiber column hemoperfusion, and methylprednisolone infusion, his general condition gradually deteriorated. He died of respiratory failure on day 129. Pathology findings of the lungs during autopsy showed diffuse alveolar damage. To our knowledge, this is the first report of severe respiratory failure after type B influenza infection. Clinicians should be aware of the potential for fatal respiratory failure in cases of type B as well as type A influenza infections.

【 授权许可】

CC BY-NC   
© 2015 The Authors. Respirology Case Reports published by John Wiley & Sons Ltd on behalf of The Asian Pacific Society of Respirology.

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