Portal Hypertension: Pathophysiology, Diagnosis, and Treatment

Journal of Veterinary Internal Medicine

S. Buob¹  A.N. Johnston¹ 

[1]Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA.

关键词: Ascites;    Cirrhosis;    Hepatic disease;    Portosystemic shunts;   

DOI  :  10.1111/j.1939-1676.2011.00691.x

来源: Wiley

【 摘 要 】

Abstract

Portal hypertension (PH) is the result of increased vascular resistance in the portal circulation, increased portal venous blood flow, or both. In veterinary medicine, where portal pressure is seldom measured directly, the diagnosis of PH often is inferred from identification of associated complications including multiple acquired portosystemic shunts, ascites, and hepatic encephalopathy. Likewise, treatment of PH primarily is aimed at controlling these complications. The goal of this review is to provide an update on the pathophysiology, diagnosis, and treatment of PH. The review draws from information in the veterinary hepatology literature, reviews, and consensus statements in human hepatology and the literature on experimental models of PH.

【 授权许可】

Unknown   
Copyright © 2011 by the American College of Veterinary Internal Medicine