Primary inflammatory myofibroblastic tumor of the diaphragm: Report of a case

Thoracic Cancer

Junke Fu¹  Qifei Wu¹  Yong Zhang¹  Xufeng Zhang² 

[1] Department of Thoracic Surgery, the First Affiliated Hospital of Medical Collage, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China;Department of Hepatobiliary Surgery, the First Affiliated Hospital of Medical Collage, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China

关键词: Diaphragm;    inflammatory myofibroblastic tumor;    surgery;   

DOI  :  10.1111/j.1759-7714.2012.00155.x

来源: Wiley

【 摘 要 】

Abstract

We report a case of primary inflammatory myofibroblastic tumor of the diaphragm in a 64-year-old man. The patient was hospitalized for a computed tomography (CT)-detected large tissue mass at the left lower lung field. Complete tumor excision followed by pathological investigation was performed. Microscopically, the tumor showed staggered arrangements of spindle myoepithelial cells, lymphoblastic and eosinophil cells. Immunohistochemically, the proliferating spindle cells showed positive staining for smooth muscle actin, vimentin, CD68 and Desmin, but negative for cytokeratin, leukocyte common antigen, epithelial membrane antigen, and S-100. This is the first reported inflammatory myofibroblastic tumor of the diaphragm found in an adult. The postoperative course was uneventful and the patient had no recurrence 18 months after surgery.

【 授权许可】

Unknown   
© 2012 Tianjin Lung Cancer Institute and Wiley Publishing Asia Pty Ltd