Motor cortical function and the precision grip

Physiological Reports

Nimeshan Geevasinga²  Parvathi Menon²  Matthew C. Kiernan¹ 

[1] The Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia;Sydney Medical School Westmead, University of Sydney, Sydney, NSW, Australia

关键词: Cortical excitability;    power grip;    precision grip;   

DOI  :  10.14814/phy2.12120

来源: Wiley

【 摘 要 】

Abstract

While task-dependent changes in motor cortical outputs have been previously reported, the issue of whether such changes are specific for complex hand tasks remains unresolved. The aim of the present study was to determine whether cortical inhibitory tone and cortical output were greater during precision grip and power grip. Motor cortex excitability was undertaken by using the transcranial magnetic stimulation threshold tracking technique in 15 healthy subjects. The motor-evoked potential (MEP) responses were recorded over the abductor pollicis brevis (APB), with the hand in the following positions: (1) rest, (2) precision grip and (3) power grip. The MEP amplitude (MEP amplitude _REST 23.6 ± 3.3%; MEP amplitude _{PRECISION GRIP} 35.2 ± 5.6%; MEP amplitude _{POWER GRIP} 19.6 ± 3.4%, F = 2.4, P < 0.001) and stimulus-response gradient (SLOPE_REST 0.06 ± 0.01; SLOPE_{PRCISION GRIP} 0.15 ± 0.04; SLOPE _{POWER GRIP} 0.07 ± 0.01, P < 0.05) were significantly increased during precision grip. Short interval intracortical inhibition (SICI) was significantly reduced during the precision grip (SICI _REST 15.0 ± 2.3%; SICI _{PRECISION GRIP} 9.7 ± 1.5%, SICI _{POWER GRIP} 15.9 ± 2.7%, F = 2.6, P < 0.05). The present study suggests that changes in motor cortex excitability are specific for precision grip, with functional coupling of descending corticospinal pathways controlling thumb and finger movements potentially forming the basis of these cortical changes.

【 授权许可】

CC BY   
© 2014 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

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