Demonstration program of population‐based lung cancer screening in China: Rationale and study design

Thoracic Cancer

Qinghua Zhou⁵  Yaguang Fan⁵  Ning Wu²  Yunchao Huang³  Ying Wang⁷  Lu Li⁴  Jiewei Liu⁴  Xinyun Wang⁶  Weimin Li¹ 

[1] Department of Respiratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China;Department of Diagnostic Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Cancer Hospital, Beijing, China;Department of Thoracic Surgery, the Third Affiliated Hospital of Kunming Medical College (Yunnan Tumor Hospital), Kunming, Yunnan, China;Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China;Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Environment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China;Department of Pathology, Tianjin Medical University General Hospital, Tianjin, China;Department of Radiology, Tianjin Medical University General Hospital, Tianjin, China

关键词: Feasibility study;    lung cancer;    mass screening;    spiral computed tomography;   

DOI  :  10.1111/1759-7714.12078

来源: Wiley

【 摘 要 】

Abstract

Background

Lung cancer is the leading cause of cancer-related death and has become an enormous economic burden in China. Low-dose spiral computed tomography (LDCT) screening could reduce lung cancer mortality. The feasibility of conducting a population-based lung cancer screening with LDCT in China is uncertain.

Methods

In 2010, a demonstration program of lung cancer screening was initiated in China. High-risk individuals were enrolled in a cluster sampling design in different centers. Participants received baseline and annual screening with spiral CT and follow-up information was collected. The objective of this program is to evaluate the feasibility of conducting population-based LDCT lung cancer screening in the Chinese context. The rates of detection, early diagnosis and treatment are defined as indicators of program performance. The optimal management strategies for nodules are explored in the Chinese context based on experiences in other studies overseas.

Results

A demonstration program of ongoing prospective, multi-center, population-based lung cancer screening is being performed in China.

Conclusions

This demonstration program will provide opportunities to explore the feasibility of LDCT lung cancer screening in the Chinese setting.

【 授权许可】

CC BY   
© 2013 The Authors. Thoracic Cancer published by Tianjin Lung Cancer Institute and Wiley Publishing Asia Pty Ltd.

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.