A Highly Selective and Sensitive Turn‐On Fluorescent Chemosensor Based on Rhodamine 6G for Iron(III)

ChemistryOpen

Prof.𠁝r. Zhi-Qiang Hu²  Ying-Ying Gu¹  Wen-Zhou Hu¹  Lei-Li Sun¹  Jiang-Hua Zhu¹ 

[1] College of Chemistry & Molecular Engineering, Qingdao University of Science & Technology, Qingdao 266042 (P. R. China);E-mail address: 关键词: chemosensors;    fluorescence;    iron(III);    rhodamine;    selective response;   

DOI  :  10.1002/open.201402065

来源: Wiley

【 摘 要 】

Abstract

Recently, more and more rhodamine derivatives have been used as fluorophores to construct sensors due to their excellent spectroscopic properties. A rhodamine-based fluorescent and colorimetric Fe³⁺ chemosensor 3’,6’-bis(ethylamino)-2-acetoxyl-2’,7’-dimethyl-spiro[1H-isoindole-1,9’-[9H]xanthen]-3(2H)-one (RAE) was designed and synthesized. Upon the addition of Fe³⁺, the dramatic enhancement of both fluorescence and absorbance intensity, as well as the color change of the solution, could be observed. The detection limit of RAE for Fe³⁺ was around 7.98 ppb. Common coexistent metal ions showed little or no interference in the detection of Fe³⁺. Moreover, the addition of CN⁻ could quench the fluorescence of the acetonitrile solution of RAE and Fe³⁺, indicating the regeneration of the chemosensor RAE. The robust nature of the sensor was shown by the detection of Fe³⁺ even after repeated rounds of quenching. As iron is a ubiquitous metal in cells and plays vital roles in many biological processes, this chemosensor could be developed to have applications in biological studies.

【 授权许可】

CC BY-NC-ND   
© 2014 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.