Molecular characteristics of residual cancer and stromal cells after chemoradiotherapy for gastric cancer: report of four cases

Clinical Case Reports

Koji Tanaka¹  Yasuhiko Mohri¹  Yuhki Koike¹  Yoshinaga Okugawa¹  Yuji Toiyama¹  Masaki Ohi¹  Minako Kobayashi¹  Yasuhiro Inoue¹  Toshimitsu Araki¹  Keiichi Uchida¹  Chikao Miki¹ 

[1] Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Tsu, Mie, Japan

关键词: Chemoradiotherapy;    gastric cancer;    microdissection;    residual cells;   

DOI  :  10.1002/ccr3.68

来源: Wiley

【 摘 要 】

Key Clinical Message

Four patients with gastric cancer underwent 5-fluorouracil and cisplatin-based chemoradiotherapy followed by surgery. Expression analysis of chemoradiosensitivity related genes in residual cancer using formalin-fixed paraffin-embedded specimens may be useful when determining a chemotherapy regimen for disease recurrence after chemoradiotherapy for gastric cancer.

【 授权许可】

CC BY-NC-ND   
© 2014 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.