Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia

Clinical Case Reports

Martin Whyte²  Alberto Quaglia¹ 

[1] Department of Pathology, King's College NHS Trust, London, UK;Department of Diabetes, King's College NHS Trust, London, UK

关键词: detemir;    hepatoselective;    NAFLD;    hypertriglyceridaemia;   

DOI  :  10.1002/ccr3.458

来源: Wiley

【 摘 要 】

Key Clinical Message

Insulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain. We describe a relative lack of effectiveness of detemir in patients with significant NAFLD and hypertriglyceridemia, compared to isophane insulin. This may affect how such patients are managed with insulin.

【 授权许可】

CC BY-NC-ND   
© 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.