Follicular lymphoma (in situ) pattern in the bone marrow: does it indicate an early stage in disease evolution?

Clinical Case Reports

Bachir Alobeid²  John Gregory Mears¹ 

[1] Division of Hematology/Oncology, Department of Medicine, Columbia University Medical Center-New York Presbyterian Hospital, New York City, New York;Division of Hematopathology, Department of Pathology and Cell Biology, Columbia University Medical Center-New York Presbyterian Hospital, New York City, New York

关键词: BCL2;    bone marrow;    CD10;    follicular colonization;    follicular lymphoma;    in situ;   

DOI  :  10.1002/ccr3.271

来源: Wiley

【 摘 要 】

Key Clinical Message

Bone marrow involvement by an isolated interstitial lymphoid aggregate exhibiting the pattern and phenotype described for follicular lymphoma in situ (FLIS) has not been reported before. The detection of clinically silent FL in this case highlights the necessity of complete staging workup when such lesions are encountered in biopsies.

【 授权许可】

CC BY-NC   
© 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

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