Induction with azacytidine followed by allogeneic hematopoietic stem cell transplantation in a Jehovah's Witness with acute monocytic leukemia

Clinical Case Reports

Hege Garelius¹  Sofia Grund¹ 

[1] Section for Haematology and Coagulation, Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden

关键词: Acute myeloid leukemia;    allogeneic transplantation;    azacitidine;    Jehovah's Witnesses;   

DOI  :  10.1002/ccr3.212

来源: Wiley

【 摘 要 】

Key Clinical Message

We have used a hypomethylating agent instead of conventional chemotherapy to induce remission in a young Jehovah's Witness with acute monocytic leukemia to avoid severe myelosuppression and blood product support. The treatment was consolidated with reduced intensity allogeneic stem cell transplantation. This could be an alternative when transfusions must be avoided.

【 授权许可】

CC BY-NC   
© 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

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