Epidemiological study of soft‐tissue sarcomas in Ireland

Cancer Medicine

Nikita Bhatt⁶  Sandra Deady⁷  Amy Gillis⁶  Alexia Bertuzzi⁴  Aurelie Fabre¹  Eric Heffernan⁵  Charles Gillham²  Gary O'Toole³ 

[1] Department of Histopathology, St. Vincent's University Hospital, Dublin, Ireland;Department of Radiation Oncology, St Luke's Hospital, Dublin, Ireland;Department of Orthopaedics, St. Vincent's University Hospital, Dublin, Ireland;Department of Medical Oncology, Adelaide and Meath Hospital, Tallaght, Dublin, Ireland;Department of Radiology, St. Vincent's University Hospital, Dublin, Ireland;Department of Surgery, Adelaide and Meath Hospital, Tallaght, Dublin, Ireland;National Cancer Registry Ireland, Cork, Ireland

关键词: Incidence;    rare cancers;    soft‐tissue sarcomas;    survival;   

DOI  :  10.1002/cam4.547

来源: Wiley

【 摘 要 】

Abstract

Soft-tissue sarcomas (STS) account for 1% of adult and 7% of pediatric malignancies. Histopathology and classification of these rare tumors requires further refinements. The aim of this paper is to describe the current incidence and survival of STS from 1994 to 2012 in Ireland and compare these with comparably coded international published reports. This is a retrospective, population study based on the data from the National Cancer Registry of Ireland (NCRI). Incidence and relative survival rates for STS in Ireland were generated. Incidence of STS based on gender, age and anatomical location was examined. Annual mean incidence rate (European Age Standardized) in Ireland between 1994 and 2012 was 4.48 ± 0.15 per 100,000 person-years. The overall relative 5-year survival rate of STS for the period 1994–2011 in Ireland was 56%, which was similar to that reported in the U.K. but lower than in most of Europe and U.S.A. Survival rate fluctuated over the period examined, declining slightly in females but showing an increase in males. STS incidence trends in Ireland were comparable to international reports. Survival trends of STS were significantly different between Ireland and other European countries, requiring further study to understand causation.

【 授权许可】

CC BY   
© 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

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