Proceedings of the Indo‐U.S. bilateral workshop on accelerating botanicals/biologics agent development research for cancer chemoprevention, treatment, and survival

Cancer Medicine

Nagi B. Kumar¹⁷  Medha Dhurandhar⁴  Bharat Aggarwal¹⁶  Shrikant Anant¹⁸  Kenyon Daniel¹⁷  Gary Deng⁷  Julie Djeu¹⁷  Jinhui Dou¹¹  Ernest Hawk¹⁶  B. Jayaram⁶  Libin Jia¹⁴  Rajendra Joshi¹³  Madhuri Kararala^3,17  Devarajan Karunagaran^8,17  Omer Kucuk^10,17  Lalit Kumar^9,17  Mokenge Malafa¹⁷  G. J. Samathanam^5,17  Fazlul Sarkar^1,17  Maqsood Siddiqi^12,17  Rana P. Singh^15,17  Anil Srivastava^2,17 

[1] Barbara Ann Karmanos Cancer Institute, Detroit, Michigan;Open Health Systems Laboratory at Johns Hopkins Montgomery County Campus, Rockville, Maryland;University of Michigan, Ann Arbor, Michigan;Centre for Development of Advanced Computing, Pune University, Pune, India;Department and Transfer Division, Department of Science and Technology, Government of India, India;India Institute of Technology-Delhi, New Delhi, India;Memorial Sloan-Kettering Cancer Center, New York, New York;Department of Biotechnology, India Institute of Technology – Madras, Chennai, India;Institute Rotary Cancer Hospital (IRCH), All India Institute of Medical Sciences, New Delhi, India;Emory Healthcare, The Emory Clinic Winship Cancer Institute, NE Atlanta, Georgia;Food and Drug Administration, Silver Springs, Maryland;Cancer Foundation of India, Tiljala, Kolkata, India;Bioinformatics Scientific and Engineering Computing, Pune University, Pune, India;National Cancer Institute, NIH, Bethesda, Maryland;School of Life Sciences, Central University of Gujarat, Gujarat, India;The University of Texas, M.D. Anderson Cancer Center, Houston, Texas;Moffitt Cancer Center, Tampa, Florida;The University of Kansas Medical Center, Kansas City, Kansas

关键词: Biologics;    botanicals;    cancer;    chemoprevention;    drug development;   

DOI  :  10.1002/cam4.42

来源: Wiley

【 摘 要 】

Abstract

With the evolving evidence of the promise of botanicals/biologics for cancer chemoprevention and treatment, an Indo-U.S. collaborative Workshop focusing on “Accelerating Botanicals Agent Development Research for Cancer Chemoprevention and Treatment” was conducted at the Moffitt Cancer Center, 29–31 May 2012. Funded by the Indo-U.S. Science and Technology Forum, a joint initiative of Governments of India and the United States of America and the Moffitt Cancer Center, the overall goals of this workshop were to enhance the knowledge (agents, molecular targets, biomarkers, approaches, target populations, regulatory standards, priorities, resources) of a multinational, multidisciplinary team of researcher's to systematically accelerate the design, to conduct a successful clinical trials to evaluate botanicals/biologics for cancer chemoprevention and treatment, and to achieve efficient translation of these discoveries into the standards for clinical practice that will ultimately impact cancer morbidity and mortality. Expert panelists were drawn from a diverse group of stakeholders, representing the leadership from the National Cancer Institute's Office of Cancer Complementary and Alternative Medicine (OCCAM), NCI Experimental Therapeutics (NExT), Food and Drug Administration, national scientific leadership from India, and a distinguished group of population, basic and clinical scientists from the two countries, including leaders in bioinformatics, social sciences, and biostatisticians. At the end of the workshop, we established four Indo-U.S. working research collaborative teams focused on identifying and prioritizing agents targeting four cancers that are of priority to both countries. Presented are some of the key proceedings and future goals discussed in the proceedings of this workshop.

【 授权许可】

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© 2012 The Authors. Cancer Medicine published by Blackwell Publishing Ltd.

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