Serum Vitamin D Level and the Risk of Urinary Tract Infection in Children: A Systematic Review and Meta-Analysis

Frontiers in Public Health

Xiaoyan Li¹  Biyu Zhang¹  Feng Qin¹  Qing Yu¹  Yanming Lu² 

[1]Department of Pediatrics, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

[2]null

关键词: urinary tract infection;    vitamin D;    children;    meta-analysis;    UTI;   

DOI  :  10.3389/fpubh.2021.637529

来源: Frontiers

【 摘 要 】

This systematic review and meta-analysis aimed to evaluate the association between serum vitamin D concentration and the risk of urinary tract infection (UTI) in children. Human studies reported the serum vitamin D level in children with UTI and healthy controls were collected from PubMed, Scopus, Embase, and Cochrane databases. The strictly standardized mean difference (SSMD) and 95% confidence interval (CI) were calculated to evaluate the relationship between serum vitamin D levels and risk of UTI. The results of analysis showed that serum vitamin D levels in children with UTI were significantly lower than healthy control children (SSMD: 0.891, 95% CI: 0.707–1.075, p < 0.000; SSMD: 0.797, 95% CI: 0.500–1.094, p < 0.000, respectively). It can be concluded that there is a significant negative relationship between serum vitamin D level and risk of UTI in children.

【 授权许可】

CC BY