Gut Microbiota and Diarrhea: An Updated Review

Frontiers in Cellular and Infection Microbiology

Zhengfeng Fang¹  Yunxia Li²  Saiming Gong²  Jie Ma²  Xiaohan Jiang²  Siting Xia²  Jie Yin²  Can Feng²  Yulong Yin³ 

[1] Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China;Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha, China;Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha, China;Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, China;

关键词: intestinal health;    fecal microbiota transplantation;    probiotics;    gut microbiota;    diarrhea;   

DOI  :  10.3389/fcimb.2021.625210

来源: Frontiers

【 摘 要 】

Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotypes. Of relevance, reprograming gut microbiota communities by dietary probiotics or fecal bacteria transplantation are widely introduced to treat or prevent diarrhea. In this review, we discussed the influence of the gut microbiota in the infection of diarrhea pathogens, and updated the research of reshaping the gut microbiota to prevent or treat diarrhea for the past few years. Together, gut microbiota manipulation is of great significance to the prevention and treatment of diarrhea, and further insight into the function of the gut microbiota will help to discover more anti-diarrhea probiotics.

【 授权许可】

CC BY