The Evolving Story in the Genetic Analysis for Heart Failure

Frontiers in Cardiovascular Medicine

Kazuo Miyazawa¹  Kaoru Ito² 

[1] Laboratory for Cardiovascular Genomics and Informatics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan;null;

关键词: heart failure;    cardiomyopathy;    genetic architecture;    genome-wide association study;    big data;   

DOI  :  10.3389/fcvm.2021.646816

来源: Frontiers

【 摘 要 】

Genomic studies of cardiovascular diseases have achieved great success, not only in Mendelian genetic diseases such as hereditary arrhythmias and cardiomyopathies, but also in common diseases such as ischemic heart disease and atrial fibrillation. However, only limited success has been achieved in heart failure due to the complexity of its disease background. In this paper, we will review the genetic research for heart failure to date and discuss how we can discover new aspects of heart failure from the viewpoint of genomic perspective.

【 授权许可】

CC BY