Endogenous Opioid Levels Do Not Correlate With Itch Intensity and Therapeutic Interventions in Hepatic Pruritus

Frontiers in Medicine

Andreas E. Kremer¹  Miriam M. Düll¹  Katharina Wolf¹  Marcel Vetter¹  Markus F. Neurath²  Peter Dietrich³ 

[1] Department of Medicine 1, University Hospital Erlangen and Translational Research Center, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany;Department of Medicine 1, University Hospital Erlangen and Translational Research Center, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany;Deutsches Zentrum Immuntherapie DZI, Erlangen, Germany;Department of Medicine 1, University Hospital Erlangen and Translational Research Center, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany;Emil-Fischer-Zentrum, Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany;

关键词: endorphin;    dynorphin;    enkephalin;    rifampicin;    bezafibrate;    cholestasis;    liver;    therapy;   

DOI  :  10.3389/fmed.2021.641163

来源: Frontiers

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