Case Report: Streptococcus alactolyticus as a Rare Pathogen of Mitral Endocarditis

Frontiers in Cardiovascular Medicine

Antonio De Bellis¹  Gianmarco Toto²  Mizar D'Abramo²  Silvia Romiti²  Valeria Santamaria²  Ernesto Greco²  Mattia Vinciguerra²  Giuseppe Sangiorgi³  Gloria Taliani⁴ 

[1] Department of Cardiology and Cardiac Surgery, Casa di Cura “S. Michele”, Maddaloni, Italy;Department of Clinical, Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy;Division of Cardiology, Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy;Hepatology Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy;

关键词: infective endocarditis;    Streptococcus alactolyticus;    mitral valve;    mitral valve regurgitation;    Streptococcus bovis;   

DOI  :  10.3389/fcvm.2021.648213

来源: Frontiers

【 摘 要 】

Streptococcus bovis/Streptococcus equinus complex (SBSEC) is a group of non-enterococcal group D Streptococci that colonizes both humans and animals. Due to gastrointestinal disease, they can switch in opportunistic pathogens passing through intestinal mucosal barrier and may cause bacteremia and distant organs damage. Despite infective endocarditis (IE), extra-cardiac manifestations of organs damage include osteoarticular infections, meningitis, and biliary infections among others; moreover, the association with colonic pathological lesions has been largely described. Streptococcus alactolyticus as a species included in SBSEC may share pathophysiological similarities, although it represents an extremely rare cause of distant organ infections, being reported in literature as causative agent of IE in only two other cases. We describe a case of 69-year-old male admitted to our institution due to mild–moderate dyspnea and fever, affected by cervico-brachialgia for 3 weeks. Streptococcus alactolyticus was identified as causative agent of IE on the mitral valve, causing severe regurgitation.

【 授权许可】

CC BY