Downregulation of Endothelial Plexin A4 Under Inflammatory Conditions Impairs Vascular Integrity

Frontiers in Cardiovascular Medicine

Caroline Suzanne Bruikman¹  Gerard Kornelis Hovingh²  Rudmer Johannes Postma³  Dianne Vreeken³  Wendy Stam³  Janine Maria van Gils³  Huayu Zhang³  Zsófia Nagy³  Stefan Martinus Leonardus Cox³  Anton Jan van Zonneveld³ 

[1] Amsterdam Cardiovascular Sciences, Department of Vascular Medicine, Amsterdam UMC, Amsterdam, Netherlands;Amsterdam Cardiovascular Sciences, Department of Vascular Medicine, Amsterdam UMC, Amsterdam, Netherlands;Novo Nordisk A/S, Copenhagen, Denmark;Department of Internal Medicine (Nephrology) and the Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, Netherlands;

关键词: neuroimmune guidance cues;    plexin;    semaphorin;    inflammation;    endothelial function;    atherosclerosis;   

DOI  :  10.3389/fcvm.2021.633609

来源: Frontiers

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