Serial EXTEM, FIBTEM, and tPA Rotational Thromboelastometry Observations in the Maastricht Intensive Care COVID Cohort—Persistence of Hypercoagulability and Hypofibrinolysis Despite Anticoagulation

Frontiers in Cardiovascular Medicine

Henri M. H. Spronk¹  Tom W. van de Berg¹  Iwan C. C. van der Horst²  Renske H. Olie³  Hugo Ten Cate³  Paul Verhezen⁴  Alexander S. Streng⁴  Yvonne M. C. Henskens⁴  Anne-Marije Hulshof⁵  Mark M. G. Mulder⁶  Jan-Willem E. M. Sels⁶  Bas C. T van Bussel⁷  Renée A. G. Brüggemann⁸  Bart Spaetgens⁸ 

[1] Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands;Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands;Department of Intensive Care Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands;Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands;Department of Internal Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands;Thrombosis Expert Centre Maastricht, Maastricht University Medical Centre+, Maastricht, Netherlands;Central Diagnostic Laboratory, Maastricht University Medical Centre+, Maastricht, Netherlands;Central Diagnostic Laboratory, Maastricht University Medical Centre+, Maastricht, Netherlands;Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands;Department of Intensive Care Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands;Department of Intensive Care Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands;Care and Public Health Research Institute, Maastricht University, Maastricht, Netherlands;Department of Internal Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands;

关键词: COVID-19;    fibrinolysis;    pulmonary embolism;    thromboelastometry (ROTEM®);    thrombosis;   

DOI  :  10.3389/fcvm.2021.654174

来源: Frontiers

【 授权许可】

CC BY