Enhanced mPGES-1 Contributes to PD-Related Peritoneal Fibrosis via Activation of the NLRP3 Inflammasome

Frontiers in Medicine

Baojun Ren¹  Yongle Ju¹  Xianrui Dou²  Qinghua Hu²  Lijuan Su²  Lewei Gong²  Qingkun Zheng²  Qimei Luo²  Zhanjun Jia³ 

[1] Department of Gastrointestinal Surgery, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Foshan, China;Department of Nephrology, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Foshan, China;Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China;

关键词: mPGES-1;    PGE2;    peritoneal fibrosis;    inflammation;    NLRP3 inflammasome;   

DOI  :  10.3389/fmed.2021.675363

来源: Frontiers

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