Should beta-blockers be continued as a treatment for myocardial infarction in the case of Kounis syndrome?

Annals of noninvasive electrocardiology: the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

article

Mari Amino¹  Tomokazu Fukushima²  Atsushi Uehata²  Chiemi Nishikawa²  Seiji Morita²  Yoshihide Nakagawa²  Tsutomu Murakami¹  Koichiro Yoshioka¹  Yuji Ikari¹ 

[1] Department of Cardiology, Tokai University;Department of Emergency Care Medicine, Tokai University

关键词: adrenaline;    anaphylaxis;    beta-blockers;    glucagon;    Kounis syndrome;   

DOI  :  10.1111/anec.12837

来源: Wiley

【 摘 要 】

A 71-year-old male patient reported to our hospital with anaphylactic shock, and the following two issues were focused in this case. First, he was resistant to adrenaline because of taking beta-blocker, and shock was repeated until glucagon administration was initiated. Second, he developed acute coronary syndrome. Two mechanisms contributing to Kounis syndrome were differentiated: 1) adrenaline induced coronary spasm and platelet activation or 2) a mismatch between oxygen supply and demand due to an allergic reaction. Beta-blocker therapy was discontinued because his cardiac function was preserved. Secondary preventive beta-blockers in recovering myocardial infarction with severe anaphylaxis history should be carefully considered.

【 授权许可】

Unknown