Hexamethylene-1,3-bis(cetyldimethylammonium bromide) protected low-toxicity ZnSe quantum dots as fluorescent probe for proteins

Micro & nano letters

article

Yaping Zhong¹  Chun Deng¹  Yu He¹  Yili Ge¹  Gongwu Song¹ 

[1] Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University;Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, College of Chemistry and Chemical Engineering, Hubei University

关键词: proteins;    molecular biophysics;    biochemistry;    surfactants;    radiation quenching;    fluorescence;    optical sensors;    zinc compounds;    II-VI semiconductors;    wide band gap semiconductors;    semiconductor quantum dots;    nanosensors;    detection limit;    correlation coefficient;    fluorescence intensity;    surfactant G16-6-16 protected ZnSe QD nanometre material;    fluorescence quenching;    hydrophobic effect;    bovine serum albumin;    proteins;    fluorescent probe;    low-toxicity ZnSe quantum dots;    hexamethylene-1;    3-bis(cetyldimethylammonium bromide);   

DOI  :  10.1049/mnl.2014.0698

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

A 78-year-old lady underwent extensive primary de-bulking surgery for ovarian cancer. Intraoperatively, blue-green colored urine was observed in the urinary bag (Figure 1).  There was a clear demarcation of the coloured urine sitting on top of the previously passed urine.  On this occasion, the blue green discolouration was caused by instillation of methylene blue into the ureter by the surgeon to monitor for ureteral injury. The colour of patient’s urine returned to normal after six hours. Methylene blue is moderately soluble in water and has a specific gravity of 1.335. Hence it is rare to see the layered discolouration. True blue urine is unusual as blue pigments combine with urochrome, the major contributor to urine’s normal yellow hue, to create the green color. The figure shows the three coloured layers – a top layer which is predominantly blue, due to methylene blue solution unmixed with urine, a middle layer of green caused by mixing of methylene blue with urine and a bottom layer of normal unmixed urine.  Phenol-containing drugs such as propofol can cause green discolouration of urine. Although a single dose of propofol has been reported to cause green urine, this was considered unlikely in our case as the surgeon had informed us that he was instilling methylene blue.

【 授权许可】

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