Central composite experimental design for the investigation of the influence of various conditions of anodisation on the amount of antimicrobial agent loaded on TiO 2 nanotubes

Micro & nano letters

article

M. Lotfi¹  R.E. Sabzi¹  M. Bahram¹  N. Samadi¹ 

[1] Department of Chemistry, Faculty of Science, Urmia University;Institute of Biotechnology, Urmia University

关键词: titanium compounds;    nanotubes;    anodisation;    antibacterial activity;    nanofabrication;    electrochemistry;    microorganisms;    titanium;    TiO2;    Ti;    Staphylococcus aureus bacteria;    culture test;    antibacterial activity;    water;    ammonium fluoride;    ethylene glycol;    titanium rods;    quadratic model;    antibiotic gentamicin;    titanium substrate;    titania nanotubes;    antimicrobial agent;    electrochemical anodisation;    central composite experimental design;   

DOI  :  10.1049/mnl.2014.0690

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

We report successful treatment of septic shock accompanied by disseminated intravascular coagulation (DIC) resulting from infection of liver abscess in a patient using a combination of polymyxin-B direct hemoperfusion (PMX-DHP) and recombinant thrombomodulin (rTM). Although hepatic cyst had been observed over 2 years previously, drainage was not performed due to limited findings of abscess on current abdominal computed tomography and ultrasonography. Control of the focus of infection therefore took time. After initiating PMX-DHP and rTM, arterial blood pressure increased and remained high. Combination therapy with PMX-DHP and rTM provides an effective approach for septic shock with DIC.

【 授权许可】

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