One-step synthesis of oxidation-resistant Cu@Ag core–shell nanoparticles

Micro & nano letters

article

Yujia Yuan¹  Hui Xia¹  Yu Chen¹  Ding Xie¹ 

[1] School of Physics and Electronics, Central South University

关键词: core-shell nanostructures;    nanoparticles;    copper;    silver;    nanofabrication;    oxidation;    thermal stability;    annealing;    one-step synthesis;    oxidation-resistant Cu@Ag core–shell nanoparticles;    wet chemical method;    core–shell nanostructure preparation;    environment friendly fabrication;    surface treatment;    copper particles;    coating silver;    thermal stability;    oxidation;    electrical properties;    copper nanoparticles;    spherical Cu@Ag core–shell nanoparticles;    annealing;    temperature 200 degC;    time 30 min;    Cu-Ag;   

DOI  :  10.1049/mnl.2017.0467

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Background: The folkloric use of Cochlospermum planchonii is yet to be substantiated with scientific evidence. Aim: The aqueous extract of C. planchonii leaves was evaluated for anti-diarrhoeal activity at 125, 250 and 500 mg/kg body weight in female Wistar rats. Setting: This research is a phytopharmacological investigation. Methods: Animal were monitored for indicators of diarrhoea in the 3 models after treatments. Results: An aqueous extract of C. planchonii leaves contained 10 secondary metabolites, with alkaloids (16.05 mg/L) occurring the most, whilst quinones (0.7 mg/L) were the least. The extract significantly ( p < 0.05) prolonged the onset time of diarrhoea, decreased water content, fresh weight and total number of wet faeces in a dose-dependent manner, and increased the percentage inhibition of defecation. The extract produced dose-specific changes on intestinal superoxide dismutase, glucose and reduced glutathione whereas the levels of intestinal Na + /K + -ATPase, alkaline phosphatase, catalase, nitric oxide were significantly ( p < 0.05) increased in the castor oil-induced diarrhoeal model. The masses and volumes of intestinal fluid decreased significantly ( p < 0.05) whereas the inhibition of intestinal fluid content increased like those of atropine-treated diarrhoeal rats in the enteropooling model. The extract dose-dependently decreased the distance travelled by the charcoal meal and increased the intestinal nitric oxide and acetylcholinesterase in the charcoal meal transit model. Conclusion: The aqueous extract of C. planchonii leaves exhibited anti-diarrhoeal activity via anti-motility and anti-secretory means. The flavonoids, alkaloids, tannins, phenolics and saponins might have acted to enhance the activities of Na + /K + -ATPase, antioxidant enzymes, intestinal glucose levels and the neurotransmitters.

【 授权许可】

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