Synthesis of SiO 2 @PAA microspheres and their application for controlling diisooctyl terephthalate migration from flexible PVC materials

Micro & nano letters

article

Bin Zhang¹  Jian Han¹ 

[1] Zhejiang Provincial Key Laboratory of Industrial Textile Materials & Manufacturing Technology, College of Materials and Textiles, Zhejiang Sci-Tech University

关键词: silicon compounds;    filled polymers;    conducting polymers;    nanocomposites;    core-shell nanostructures;    nanofabrication;    mixtures;    silicon dioxide-PAA microspheres;    diisooctyl terephthalate migration;    flexible PVC materials;    silicon dioxide-poly(acrylic acid) microsphere;    dispersions;    polyvinyl chloride matrix;    PVC matrix;    structural properties;    mixtures;    chlorinated polyethylene;    DOTP migration;    synergistic effect;    reduction;    interface combination;    PVC-CPE-silicon dioxide-PAA composites;    core–shell structures;    nanostructured material;    SiO2;   

DOI  :  10.1049/mnl.2017.0685

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

According to previous publications, chronic uses of AEDs reduce bone health, increase homocysteine levels, alkaline phosphates and many other biochemical changes. The aim of this study was to investigate carbamazepine (CBZ) effects on bone density, serum levels of folate, vitamin B12 and other biochemical variables. Twenty-one adult epileptic patients who received CBZ for treatment of epileptic attacks were enrolled. Bone mineral density (BMD) was evaluated by dual-energy X-ray absorptiometry method. Biochemical indices of bone metabolism, including serum calcium, phosphorus, alkaline phosphatase contents and also serum levels of folate, vitamin B12, homocysteine were measured. All clinical, laboratory and pharmacological data were recorded in d-Base and analyzed using SPSS (version 16) for windows. BMD Z-scores, and 25-dihydroxyvitamin D3 concentrations was not differ significantly, but it seems that, the female patients had diminished BMD at the femoral neck ( p ≤ 0.05). Folate or vitamin B12 levels tend toward lower values. This seems to be connected to a tendency toward higher mean corpuscular volume (MCV) with a mean of 84.9 fl (ranged from 59-120 fl). TWithin the population studied, t here was no correlation between CBZC 0 and homocysteine levels ( p≤ 0.63). In compare to normal value the serum calcium content was lower with a mean of 7.8 mg/dl (ranged; 7.0-8.9 mg/dl; p ≤ 0.04). With a mean of 213 U/L serums alkaline phosphatase was significantly higher (p ≤ 0.01) than normal values. Due to the need for chronic prescription strategy in order to control convulsion attack, pharmacotherapy with AEDs may consequence to changes in serum contents of calcium, phosphorus, alkaline phosphatase in addition to decrease in BMD and increase in homocysteine levels. Further studies related to efficacy and side-effects of CBZ as the most prescribed AEDs in Iranian epileptic population seem to be valuable.

【 授权许可】

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