Micro & nano letters | |
Electromagnetic interference shielding properties of graphene/MWCNT hybrid buckypaper | |
article | |
Shaowei Lu1  Dandan Chen1  Junyan Shao1  Yaoyao Bai1  Caijiao Tian1  Keming Ma1  Xiaoqiang Wang1  | |
[1] Faculty of Aerospace Engineering at Shenyang Aerospace University (SAU) | |
关键词: electromagnetic shielding; nanofabrication; electromagnetic wave absorption; nanocomposites; multi-wall carbon nanotubes; graphene; electrical conductivity; electromagnetic interference; electromagnetic wave reflection; EMI SE; SE absorption; SE reflection; electromagnetic interference shielding; graphene-MWCNT hybrid buckypaper; multiwalled carbon nanotube; electrical conductivity; frequency 8.0 GHz; C; | |
DOI : 10.1049/mnl.2018.5066 | |
学科分类:计算机科学(综合) | |
来源: Wiley | |
【 摘 要 】
Solid dispersion is an attractive tool of pharmaceutical technology used to improve the physical properties of drugs. Among these properties is to enhance the solubility of the drugs.Rebamipide is a poorly soluble drug of class IV of biopharmaceutical classification system (BCS).Rebamipide is used as potent antiulcer, mucoprotective drug, by stimulating the generation of prostoglandine enhanced mucosal protection.Rebamipide was formulated as a solid dispersion using different polymers such as pluronic F-127, PEG6000, PVP K30, and TPGS by using different preparation methods solvent evaporation, fusion, and kneading methods.It was seen that rebamipide was successfully dispersed in a homogenous solid dispersion matrix by solvent evaporation method using TPGS (1:15) drug carrier ratio.Moreover, the results revealed that the solubility of rebamipide (23.9µg/ml) increased significantly (p?0.05) by 36.4 x fold to obtain 874µg/ml solubility in rebamipide matrix. On the other hand, characterization of rebamipide solid dispersion using FTIR, DSC, SEM and x-ray diffraction demonstrated no drug polymer interaction, and converting the rebamipide from crystal to amorphous state lattice.
【 授权许可】
CC BY|CC BY-ND|CC BY-NC|CC BY-NC-ND
【 预 览 】
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RO202107100003017ZK.pdf | 165KB | download |