SPR-enhanced fluorescence and protein-improved blood compatibility of quadruple core/shell nanostructure of Ag@SiO 2 @Eu 3+ (tta) 3 Phen@Protein

Micro & nano letters

article

Peipei Yan¹  Jianguo Tang¹  Yu Zhang¹  Wenfei Shen¹  Yao Wang¹  Lin Hou²  Runhua Tian²  Yanxin Wang¹  Haidong Li¹  Linjun Huang¹  Laurence A. Belfiore¹ 

[1] Institute of Hybrid Materials, National Center of International Joint Research for Hybrid Materials Technology, National Base of International Scientific & Technological Cooperation on Hybrid Materials, Qingdao University;Biochemistry and Molecular Biology Department, School of Medicine, Qingdao University;Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University;Department of Chemical and Biological Engineering, Colorado State University

关键词: coagulation;    silver;    enzymes;    surface plasmon resonance;    molecular biophysics;    fluorescence;    blood;    cellular biophysics;    biochemistry;    biomedical materials;    core-shell nanostructures;    silicon compounds;    europium compounds;    nanomedicine;    Au-SiO2;    nanomaterial;    physiological saline state;    aqueous solution;    correlation coefficients;    human blood;    clinical anticoagulation tests;    europium complexes;    surface-plasma resonance;    quadruple core-shell nanostructure;    SPR-enhanced fluorescence;    lysozyme;    triple nanostructure;    protein-improved blood compatibility;    quadruple nanostructure blood sample;   

DOI  :  10.1049/mnl.2018.5130

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Diabetes mellitus is a common health problem worldwide counting about 1.2 million cases in Iraq in 2015. Taking in account of the patient’s beliefs about the prescribed medication had been reported to be one of the most important factors that affects adherence where holding positive beliefs about medications is a prerequisite for intentional adherence. The aim of the current study was to investigate and assess beliefs about medicines among type 2 diabetic patients and to determine possible association between this belief and glycemic control as well as some patient-specific factors. This study is a cross-sectional study carried out on 380 (mean age 56.58± 10.06 years) already diagnosed T2DM patients who attended the National Diabetes Center, Al-Mustansiriya University – Baghdad/ Iraq during December-2016 to March-2017. Belief about medicine was assessed by using an arabic version of the questionnaire. The patients had a stronger agreement with the mean necessity scale (19.29) than the mean concern scale (14.27). The majority of the patients (76.3%) had strong beliefs in the necessity of anti-diabetic treatment for maintaining good control of diabetes (scores of specific-necessity was greater than score of specific-concern). However, (18.4%) of the patients reported strong concerns about the anti-diabetic treatment (scores of specific-concern greater than score of specific-necessity). The small number of the patients (5.3%), have equal scores for specific-necessity and specific-concern scores. The patient's belief about medicine was found to be poor predictor of  good glycemic control.

【 授权许可】

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