Diameter dependence of the UV light detecting performance of InGaN/GaN nanorods array photodetector

Micro & nano letters

article

Yunlong Kang¹  Ding Wang¹  Ping Wang¹  Aiying Chen¹  Huijun Li¹  Xianying Wang¹  Junhe Yang¹ 

[1] School of Materials Science and Engineering, University of Shanghai for Science & Technology;Shanghai Innovation Institute for Materials

关键词: ultraviolet detectors;    wide band gap semiconductors;    indium compounds;    nanosensors;    etching;    III-V semiconductors;    photodetectors;    semiconductor quantum wells;    nanorods;    gallium compounds;    nanofabrication;    InGaN/GaN nanorod arrays;    multiple quantum wells;    inductively coupled plasma;    anisotropic wet etching method;    ICP etch parameters;    ultraviolet detectors;    UV detecting performance;    large-scale vertical aligned MQWs nanorods array;    diameter dependence;    UV light detecting performance;    InGaN/GaN nanorods array photodetector;    size 330.0 nm to 1090.0 nm;    InGaN/GaN;   

DOI  :  10.1049/mnl.2018.5160

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

The effective surface area of drug particle is increased by a reduction in the particle size. Since dissolution takes place at the surface of the solute, the larger the surface area, the further rapid is the rate of drug dissolution. Ketoprofen     is class II type drug according to (Biopharmaceutics Classification System BCS) with low solubility and high permeability. The aim of this investigation was to increase the solubility and hence the dissolution rate by the preparation of ketoprofen     nanosuspension using solvent evaporation method. Materials like PVP K30, poloxamer 188, HPMC E5, HPMC E15, HPMC E50, Tween 80 were used as stabilizers in perpetration of different formulas of Ketoprofen     nanosuspensions. These formulas were evaluated for particle size, entrapment efficiency of drug (EE), effect of stabilizer type, effect of stabilizer concentration and in-vitro dissolution studies. All of the prepared Ketoprofen     nanosuspensions formulas showed a particle size result within Nano range. The average particle size of Ketoprofen     nanosuspensions formulas was observed from 9.4 nm to 997 nm. Entrapment efficiency was ranged from 79.23% to 95.41 %. The in vitro dissolution studies showed a significant (p<0.01) enhancement in dissolution rate of nanosuspension formulas compared to pure drug (drug alone) and physical mixture (drug and stabilizer). The results indicate the suitability of solvent evaporation method for Ketoprofen with improved in vitro dissolution rate and thus perhaps enhance fast onset of action for drug.

【 授权许可】

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