Antibacterial and photocatalytic activity of anatase phase Ag-doped TiO 2 nanoparticles

Micro & nano letters

article

Mahsa Madadi¹  Mohammad Ghorbanpour¹  Atabak Feizi² 

[1] Department of Chemical Engineering, University of Mohaghegh Ardabili;Department of Civil Engineering, University of Mohaghegh Ardabili

关键词: catalysis;    nanofabrication;    nanoparticles;    semiconductor materials;    particle size;    photochemistry;    titanium compounds;    X-ray chemical analysis;    scanning electron microscopy;    silver;    doping profiles;    visible spectra;    ultraviolet spectra;    X-ray diffraction;    antibacterial activity;    semiconductor doping;    antibacterial activity;    silver-doped titanium dioxide;    solar light-induced photocatalytic applications;    agglomerated spherical particles;    photocatalytic activity;    doping;    UV-vis DRS;    anatase phase Ag-doped TiO2 nanoparticles;    solid-state molten-salt method;    EDX;    SEM;    ultraviolet-visible diffusive reflectance spectrometry;    scanning electron microscopy;    powder X-ray diffraction;    visible absorption capability;    light irradiation;    TiO2Ag;   

DOI  :  10.1049/mnl.2018.5057

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

On the basis of known coumarin-based prodrug system, a novel coumarin-based mutual prodrug of 5-fluorouracil and dichloroacetic acid was designed, synthesized and evaluated as a promising oral chemotherapeutic agent basing on in vitro stability study in HCl buffer (pH 1.2) and in phosphate buffer (pH 7.4), as well as in vitro release study in human serum. The chemical structure of prodrug was confirmed by analyzing its FTIR, 1H NMR, 13C NMR and MS-ESI spectra. The results of in vitro kinetic study indicated that the prodrug was significantly stable in HCl and in phosphate buffers, and was hydrolyzed in human serum followed pseudo first order kinetics.

【 授权许可】

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