Effect of different carbon supporter on the Ni/C catalyst for water oxidation

Micro & nano letters

article

Ke Wang¹  Zhiyan Sun²  Yan Zhu¹  Li Chunhui¹ 

[1] School of Chemistry and Molecular Engineering, Zhengzhou University;Department of Orthopaedics, the 153rd Central Hospital of PLA

关键词: carbon;    nickel compounds;    nanocomposites;    current density;    graphene;    nanoparticles;    catalysis;    electrochemical electrodes;    nickel;    electrochemistry;    hydrophilicity;    electrolytes;    catalysts;    reduction (chemical);    oxidation;    nanofabrication;    NiOOH;    Ni-C;    Ni/C catalyst;    water oxidation;    Ni-based nanomaterials;    alkaline electrolytes;    Ni nanoparticles;    Ni/C nanocomposite;    surface hydrophilism;    catalytically active species;    catalytic kinetics difference;    electrochemical catalysts;    OER catalysts;    current density;    Tafel slope;    structure–property relationship;    nitrogen-doped reduced graphene oxide;    oxygen evolution reaction;   

DOI  :  10.1049/mnl.2018.5367

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

A group of amine derivatives [4-aminobenzenesulfonamide derivatives, 2-aminopyridine and 2-aminothiazole] incorporated to α-carbon of diclofenac a well known non-steroidal anti-inflammatory drug (NSAID) to increase bulkiness were designed and synthesized for evaluation as  a potential anti-inflammatory agents with expected COX-2 selectivity. In vivo acute anti-inflammatory activity of the selected final compounds (9, 12 and 13) was evaluated in rats using egg-white induced edema model of inflammation in a dose equivalent to (3 mg/Kg) of diclofenac sodium. All tested compounds  produced a significant reduction  in paw edema with respect to the effect of propylene glycol 50% v/v (control group). Moreover, the 4-aminobenzenesulfonamide derivative (compound 9) exhibited superior anti-inflammatory activity compared to diclofenac sodium at times 180-300 minutes with the same onset of action. The results of this study indicate that the incorporation of the selected aromatic amino groups in to diclofenac maintain its anti-inflammatory activity.

【 授权许可】

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