Preparation of GCE modified with ZnO@CoFe 2 O 4 magnetic nanoparticles and its application in electrocatalytic determination of Acetaminophen

Micro & nano letters

article

Karim Asadpour-Zeynali¹  Nasrin Lotfi¹ 

[1] Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz

关键词: zinc compounds;    nanocomposites;    pH;    oxidation;    electrochemical electrodes;    catalysis;    nanoparticles;    II-VI semiconductors;    nanofabrication;    electrochemical sensors;    ferrites;    scanning electron microscopy;    voltammetry (chemical analysis);    nanosensors;    carbon;    ZnO;    CoFe2O4;    size 9.53 mum to 47.0 mum;    size 0.36 mum;    differential pulse-voltammetry;    cyclic voltammetry;    energy dispersive X-ray;    scanning electron microscopy;    nanosensor;    electrocatalytic determination;    ZnO@CoFe2O4 magnetic nanoparticles;    GCE preparation;    AC oxidation;    ZnO nanoparticles;    acetaminophen sensing;    facile preparation method;    cobalt;   

DOI  :  10.1049/mnl.2019.0463

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

In this work, a nanocomposite of zinc oxide (ZnO) and cobalt ferrite (CoFe 2 O 4 ) was synthesised with a facile preparation method in order to fabricate a nanosensor for acetaminophen (AC) sensing. The ZnO nanoparticles were electrochemically deposited onto glassy carbon electrode (GCE) coated with magnetic nanoparticles CoFe 2 O 4 . The morphology and structure of ZnO@CoFe 2 O 4 nanocomposite were investigated by scanning electron microscopy and energy dispersive X-ray. The performance of the proposed sensor was characterised with cyclic voltammetry and differential pulse-voltammetry techniques. The ZnO@CoFe 2 O 4 /GCE nanosensor shows excellent electrocatalytic activity for AC oxidation in phosphate buffer (pH = 7) solution and it exhibits a good linear relationship and the low limit of detection (LOD). The ZnO@CoFe 2 O 4 /GCE showed good sensitivity, selectivity, stability, reproducibility, larger specific area and fast response in comparison with other reported sensors. The result calibration diagram of using the differential pulse-voltammetric technique has two linear ranges of 0.495–9.53 and 9.53–47.00 µm, and the LOD for AC by this method obtained 0.36 µm. The performance of this modified electrode was evaluated for measuring AC in some pharmaceutical formulations.

【 授权许可】

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