| Energy Conversion and Economics | |
| Multi-scene upgrade and renovation method of existing park-level integrated energy system based on comprehensive analysis | |
| article | |
| Yan Cao1  Yunfei Mu1  Hongjie Jia1  Yan Qi2  Congshan Wang1  | |
| [1] Key Laboratory of Smart Grid of Ministry of Education, Tianjin University;Electric Power Research Institute, State Grid Tianjin Electric Power Company | |
| 关键词: Respiratory Distress Syndrome; Preterm; Surfactant; MIST; InsurE"/>; | |
| DOI : 10.1049/enc2.12014 | |
| 学科分类:生物科学(综合) | |
| 来源: Wiley | |
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【 摘 要 】
Background: The present study was conducted to investigate and compare the effectiveness of the minimally invasive surfactant therapy (MIST) and the INSURE technique (Intubation, Surfactant administration, and extubation) in spontaneously breathing preterm infants. Methods: Preterm infants (28-34 weeks of gestation) born with respiratory distress syndrome between April 2013 and February 2014 were randomly selected to receive 200 mg/kg of surfactant (Curosurf) using either MIST or INSURE techniques. In the MIST group, surfactant was instilled via a thin tracheal catheter (5-f) that was then removed. In the INSURE group, the infants were first intubated, administered surfactant through passing a feeding tube through the endotracheal tube, and then extubated after 30 seconds of positive pressure ventilation. Nasal CPAP for respiratory support continued in both groups after performing the procedures. The amounts of supplemental oxygen required, intensive care requirements, and outcomes were compared between the two groups. Results: The present study examined 27 infants in the MIST group and 26 in the INSURE group. The amount of oxygen required by the MIST group was consistently less than that in the other group over the first 48 hours of life. The overall mean FiO 2 was 42.5 ± 19.6 in the MIST group and 48.4 ± 21.6 in the INSURE group (P = 0.009). The mean duration of stay in the neonatal intensive care unit was 7.3 ± 7.2 days in the MIST group and 9 ± 10.4 days in the INSURE group (P = 0.81). In terms of early and delayed complications, no differences were observed between the two groups. Conclusions: The MIST technique is a feasible and effective alternative to the INSURE technique and is advised to be performed with impunity in preterm infants (28 to 34 weeks of gestation).
【 授权许可】
CC BY|CC BY-ND|CC BY-NC|CC BY-NC-ND
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| RO202107100001508ZK.pdf | 1615KB |
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