Spot electricity market design for a power system characterized by high penetration of renewable energy generation

Energy Conversion and Economics

article

Jiajia Yang¹  Zhao Yang Dong¹  Fushuan Wen²  Qixin Chen⁴  Bomiao Liang⁵ 

[1] School of Electrical Engineering and Telecommunications, University of New South Wales;School of Electrical Engineering, Zhejiang University;Department of Electrical Power Engineering and Mechatronics, Tallinn University of Technology;State Key Laboratory of Power Systems, Department of Electrical Engineering, Tsinghua University;School of Automation and Electrical Engineering, Zhejiang University of Science and Technology

关键词: Adolescent;    Epilepsy;    Child;    Ketogenic Diet;    Aspartate Aminotransferase;    Alkaline Phosphatase;    Alanine Aminotransferase"/>;   

DOI  :  10.1049/enc2.12031

学科分类：生物科学（综合）

来源: Wiley

【 摘 要 】

Background: High-fat content and carbohydrate restriction of the ketogenic diet (KD) increases the workload of some organs, especially the liver. Moreover, most of the antiepileptic drugs (AEDs) are metabolized in the liver; therefore, the function of the liver could be influenced during the treatment with KD. This study was undertaken to investigate the influence of the ketogenic diet on liver function. Methods: A prospective, open-label study was carried out. A total of 28 patients with intractable epilepsy initiated the diet. All patients were children and adolescents who did not respond to at least 2 AEDs. Liver function tests including Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), and alkaline phosphatase (ALP) were analyzed before and after 3 months on the KD. Results: Fourteen patients with the median age of 4.12 (2.31 - 9.70) years completed the study. The serum levels of ALP and AST did not differ significantly before and after 3 months on the diet (P value > 0.05). There was a significant difference in the serum level of ALT before and after 3 months of treatment (13 vrs 20, P = 0.014). Conclusions: Albeit, it seems that KD did not have any influence on the serum levels of AST and ALP; however, it had a significant effect on the serum level of ALT. More investigations with a larger sample size and longer follow-up duration are needed to approve abovementioned results.

【 授权许可】

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