Bladder cancer invasion along a tension-free vaginal mesh

IJU Case Reports

article

Atsuhiko Ochi¹  Shunsuke Harada²  Wataru Fukuokaya¹  Koichi Honma²  Tingwen Huang¹  Hirokazu Abe¹ 

[1] Departments of Urology, Kameda Medical Center;Department of Diagnostic Pathology, Kameda Medical Center

关键词: bladder cancer;    carcinoma in situ;    laparoscopic radical cystectomy;    pelvic organ prolapse;    tension-free vaginal mesh;   

DOI  :  10.1002/iju5.12254

学科分类：社会科学、人文和艺术（综合）

来源: Wiley

【 摘 要 】

Introduction The effect of synthetic mesh after pelvic organ prolapse surgery on the progression of bladder cancer remains unclear. Case presentation A 79-year-old woman who underwent a tension-free vaginal mesh procedure 8 years prior was diagnosed with carcinoma in situ of the bladder. Although intravesical Bacillus Calmette–Guérin therapy was started, the tumor rapidly became muscle invasive. Laparoscopic radical cystectomy was performed following radiochemotherapy; however, the tumor extended to the left internal obturator muscle along the mesh arm. Pathological findings showed desmoplastic high-grade urothelial carcinoma infiltrating around the mesh. Finally, cancer recurred rapidly in the left internal obturator muscle. Conclusion Synthetic mesh can become an abnormal anatomical pathway for tumor infiltration. Therefore, in high-risk bladder cancer patients who underwent a tension-free vaginal mesh procedure, radical cystectomy should be performed without delay before the tumor invades the perivesical tissue.

【 授权许可】

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