Embryonic stem (ES) cells and induced pluripotent stem (iPS) cells in rats

Reproductive medicine and biology

article

Masumi Hirabayashi¹  Shinichi Hochi² 

[1] Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences;Division of Applied Biology, Faculty of Textile Science and Technology, Shinshu University

关键词: Embryonic stem cells Gene knock-out Organ regeneration Pluripotent stem cells Xenotransplantation;   

DOI  :  10.1007/s12522-011-0095-4

学科分类：工业工程学

来源: Wiley

【 摘 要 】

Background : Infants with low birth weight or LBW is one of the risk factors for infant mortality. Complications LBW actually can be prevented and dealt with, but is constrained by access to health care, socio-economic circumstances, a referral system that has not gone well, delays in early detection and awareness of parents to seek medical help. By looking at the number of deaths caused by LBW remains high, and research on the causes of LBW widely used partial analysis, and have not been analyzed in stages, the researchers conducted this research with multilevel analysis. Subjects and Method : This was an observational studt with case control design. A total sample of 120 infants were selected by fixed disease sampling with a ratio of 1: 2 between cases and controls. Data were analyzed using multiple logistic regression. Results : There are three variables at the individual level were significantly associated with LBW and was statistically significant can among others, mother’s education (OR= 0.19; 95% CI= 0:07 to 0.53; p= 0.001), history of ANC t (OR= 7.76; 95% CI= 2.18 to 27.62; p= 0.002) and the nutritional mother status (OR= 5.61; 95% CI= 0.21 to 0.79; p= 0.008) and the variables that are not statistically significant is the mother’s age and family income, and there are  no contextual role within house with wellness facilities with LBW expressed by ICC < 0.001. Conclusion : The influence of maternal education, a history of the ANC examination and nutritional status of mothers with LBW and there is no contextual role of distance between home and health care facilities with LBW. This study suggests to health professional to improve the coverage of the ANC.

【 授权许可】

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