Oxidative stress and redox regulation of gametogenesis, fertilization, and embryonic development

Reproductive medicine and biology

article

Satoshi Tsunoda¹  Naoko Kimura²  Junichi Fujii¹ 

[1] Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University;Laboratory of Animal Reproduction, Graduate School of Agricultural Sciences, Yamagata University

关键词: In vitro fertilization Oogenesis Oxidative stress ROS signaling Spermatogenesis;   

DOI  :  10.1007/s12522-013-0170-0

学科分类：工业工程学

来源: Wiley

【 摘 要 】

Background: Central venous pressure is often used in intensive care, especially in patients who ex­pe­rience impaired fluid balance, heart failure, evaluation of therapeutic response and media for the­­rapy or hypertonic fluid. The patient's hemodynamic condition during treatment in the intensive care unit (ICU) is con­­stantly changing (unstable), therefore, serial monitoring of central venous pressure is needed and the patient's position must be constant. Changing the position of the patient in a place is some­ti­­mes something that cannot be avoided when the patient is in intensive room. This study aimed to examine the effect of changing the position of patients in bed at 0 0 , 15 0 , 30 0 , and 45 0 on central venous pressure (CVP) va­lues.   Subjects and Method: This was quasi-experimental study, using a post test with­out control group with repeated measures. This study was conducted in the ICU/ICCU Room at Tarakan Ho­s­pital, No­rth Kalimantan, from May to June 2019. A total of 30 patients was selected by acci­den­­­tal sampling. The dependent variable was central venous pressure. The independent variable was the position of the patient when a central venous pressure examination was carried out, with the degree of positions which were 0 0 , 15 0 , 30 0 , and 45 0 . The data was obtained from observation she­et. CVP was measured by water manometer. The data were analyzed by Anova. Results: The lowest mean CVP was achieved at 0º (Mean=15.13; SD= 5.79). The highest mean CVP was achieved at 45º (Mean=18.18; SD=5.35). The different mean between 0º and 45º was sta­tis­tically significant (p=0.001). The mean CVD at 15º was mean=16.35; SD=5.73. The mean CVD at 30º was mean=17.07; SD=5.42). The different mean between 15º and 30º was statistically sig­ni­fi­cant (p=0.047).   Conclusion: The best position for perform central venous pressure is 45 o .

【 授权许可】

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