Effects of Hachimijiogan, a Kampo powder, on epididymidis sperm characteristics in healthy male rats

Reproductive medicine and biology

article

Yuying Wang¹  Chiaki Murayama²  Seiwa Michihara²  Toru R. Saito¹  Hisayoshi Norimoto³ 

[1] Behavioral Neuroscience Laboratory, Graduate School of Veterinary Medicine, Nippon Veterinary and Life Science University;Kampo Research Laboratories, Ltd.;Kampo Research Laboratories, Kracie Pharma, Ltd.

关键词: Hachimijiogan Kampo medicine Kidneyreplenishing Male infertility Sperm characteristics;   

DOI  :  10.1007/s12522-014-0191-3

学科分类：工业工程学

来源: Wiley

【 摘 要 】

Background: Melorheostosis is a rare sclerosing bone dysplasia characterized by its classic radiographic feature of flowing/dripping candle wax. It usually affects one limb, more often the lower extremity, and rarely the axial skeleton. The etiology remains unknown and various theories have been proposed to explain the pathogenesis of this disease. It often has an insidious onset in early adult life. Symptoms include pain, oedema, and limitation of joint movement. Case presentation: A patient aged 25 year old male complaint of pain on the left lower extremity for the last 3 years. There is muscle atrophy at left extremity, bowing of the thigh, awelling at the foot. There is palpable mass at the left bottom, solid consistency and fixed. There are also limitation ROM of hip, knee and ankle. From the radiography examination showed inhomogen thickening of the periosteal cortical and endosteal, dripping candle wax appearance, and sclerotic lesion at soft tissue. Conculsion: X-ray is a sufficient method for diagnosis of melorheostosis.Other imaging techniques are essential for decision about therapeutic intervention (CT or MRI). Laboratory findings are usually in physiological range. Symptomatic therapy proved to be sufficient in subjective symptoms management.

【 授权许可】

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