Update of Wnt signaling in implantation and decidualization

Reproductive medicine and biology

article

Qian Zhang¹  Junhao Yan¹ 

[1] Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University;National Research Center for Assisted Reproductive Technology and Reproductive Genetics;The Key Laboratory for Reproductive Endocrinology of Ministry of Education;Shandong Provincial Key Laboratory of Reproductive Medicine

关键词: b-Catenin Decidualization Implantation Wnt ligands Wnt signaling;   

DOI  :  10.1007/s12522-015-0226-4

学科分类：工业工程学

来源: Wiley

【 摘 要 】

Embryonic development into an implantation-competent blastocyst, synchronized uterine transformation into a receptive stage, and an intimate cross-talk between the activated blastocyst and the receptive uterus are essential for successful implantation, and therefore for subsequent pregnancy outcome. Evidence accumulating during recent years has underlined the importance of the Wnt signaling pathway in mammalian implantation and decidualization. Herein, this review focuses on the current state of knowledge regarding Wnt signaling in multiple implantation and decidualization events: pre-implantation embryo development, blastocyst activation for implantation, uterine development, and decidualization.

【 授权许可】

CC BY|CC BY-NC|CC BY-NC-ND