Anti-Müllerian hormone as a marker of ovarian reserve: What have we learned, and what should we know?

Reproductive medicine and biology

article

Akira Iwase¹  Tomoko Nakamura¹  Satoko Osuka¹  Sachiko Takikawa¹  Maki Goto¹  Fumitaka Kikkawa¹ 

[1]Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine

[2]Department of Maternal and Perinatal Medicine, Nagoya University Hospital

关键词: Anti-Mu¨llerian hormone Female reproduction Infertility Menopause Ovarian reserve;   

DOI  :  10.1007/s12522-015-0227-3

学科分类：工业工程学

来源: Wiley

【 摘 要 】

Background : Streptozotocin as diabetogenic can damage the pancreatic β cells of animals tried through the oxidative stress process to increase blood sugar levels. Giving ethanolic extract of squash fruit has hypoglycemia effect because it contains flavonoids that act as antioxidants and antihiperglichemia. This study aimed is analyze the effect of ethanol extract of squash fruit to decrease blood sugar level and the change of pancreatic β cell diameter. Subjects and Method : This study was an experimental study with post-randomized controlled group design, using male white mice (Mus musculus L.) DD Webster strains randomized into 4 groups: negative control group, positive control group, group with extract ethanol of 100 mg/ kgBB, and a group of ethanol extract of 200 mg/ kgBW of pumpkin. Results: The results showed a significant reduction in blood sugar levels if compared with the control group. The presence of changes in β pankreas cell diameter on ethanol extract of 100 mg/ kgBB and 200 mg/ kgBB. Conclusion: The conclusion of this study is the extract of ethanol fruit of 200mg/ kgBB squash significantly reduce blood sugar level of mice, the change of β pankreas cell diameter on ethanol extract of 100mg/ kgBB and 200mg/ kgBB.

【 授权许可】

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