Superior clinical pregnancy rates after microsurgical epididymal sperm aspiration

Reproductive medicine and biology

article

Hatsuki Hibi¹  Makoto Sumitomo²  Noritaka Fukunaga³  Megumi Sonohara³  Yoshimasa Asada³ 

[1] Department of Urology, Kyoritsu General Hospital;Department of Urology, Aichi Medical University School of Medicine;Asada Ladies Clinic

关键词: azoospermia;    cryopreservation;    intracytoplasmic sperm injection outcome;    microscopic epididymal sperm aspiration;    sperm retrieval;   

DOI  :  10.1002/rmb2.12069

学科分类：工业工程学

来源: Wiley

【 摘 要 】

Purpose To assess normal fertilization, clinical pregnancy, and live birth rates after the use of microscopic epididymal sperm aspiration (MESA). Methods One-hundred-and-sixty azoospermic participants who underwent MESA were evaluated. The MESA was performed by using a micropuncture method with a micropipette. In cases in which motile sperm were not obtained after the MESA, conventional or micro-testicular sperm extraction (TESE) was completed. Results Adequate motile sperm were retrieved in 71 participants by using MESA and in 59 out of 89 participants by using TESE. Of the total number of patients, 123 underwent intracytoplasmic sperm injection. After MESA, the normal fertilization rate was 73.5% and the clinical pregnancy rate per case was 95.7%. Healthy deliveries resulted after MESA in 65 (92.9%) cases and after TESE in 38 (71.7%) cases. Conclusion The MESA specimen collection does not have any special requirements, such as mincing tissue disposition. The MESA also can reduce the amount of laboratory work that is needed for cryopreservation. In the authors' experience, MESA is a beneficial procedure and should be given priority over TESE.

【 授权许可】

CC BY|CC BY-NC|CC BY-NC-ND