Equivalent clinical outcome after vitrified-thawed blastocyst transfer using semi-automated embryo vitrification system compared with manual vitrification method

Reproductive medicine and biology

article

Atsuko Miwa¹  Yukiko Noguchi²  Kayo Hosoya¹  Yuusuke Mori¹  Takuma Sato²  Yuta Kasahara²  Miwa Hidaka¹  Hiroshi Hayashi¹ 

[1] Keiai Reproductive & Endosurgical Clinic;Department of Obstetrics and Gynecology, The Jikei University School of Medicine

关键词: automated vitrification;    blastocyst;    cryopreservation;    Gavi®;    pregnancy;   

DOI  :  10.1002/rmb2.12320

学科分类：工业工程学

来源: Wiley

【 摘 要 】

Purpose: This study compared Gavi®, an automated system for the equilibration and dehydration steps of vitrification, and a manual vitrification procedure in terms of effects on clinical outcomes. Methods: The authors retrospectively compared survival rate, and clinical and perinatal outcomes after vitrified-thawed single blastocyst transfer between Gavi® (G method) in 398 cases and Cryotop® (C method) in 208 cases. Results: With C and G methods, survival rates were 98.6% (208/211) and 99.3% (398/401), total pregnancy rates were 34.3% (72/208) and 33.4% (133/398), and total miscarriage rates were 22.2% (16/72) and 24.8% (33/133), respectively. Among women .05 each). Conclusions: Gavi® showed comparable clinical outcomes to the manual vitrification method and can be considered an alternative vitrification procedure in assisted reproductive technology.

【 授权许可】

CC BY|CC BY-NC|CC BY-NC-ND